Industrial activities are increasingly dependent on each other. Several recent events (e.g. Tsunami and earthquake in Japan in 2011) illustrate the conse quences (e.g. humans, economic...) of interactions between industrial infrastructures. The state-of-the-art review focused mainly on the risk assessment and interdependencies between critical infrastructures. The aim of this paper is to present an approach able to determine an infrastructure vulnerability level and risk scenarios development based on Seveso regulations and critical infrastructures. The vulnerability infrastructure level is assessed with a multi-criteria analysis. The goal is to identify several criteria ac cording to physic, functional, economic, social and environment context of the infrastructure in the territory. The risk scenarios are developed in order to estimate the consequences in a territory of a threat on one or several infrastructures.